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Nonclassical MHC Ib-restricted CD8(+) T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection

MHC Ib-restricted CD8(+) T cells have been implicated in host defense against Mycobacterium tuberculosis (Mtb) infection. However, the relative contribution of various MHC Ib-restricted T cell populations to anti-mycobacterial immunity remains elusive. In this study, we used mice that lack MHC Ia (K...

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Detalles Bibliográficos
Autores principales: Shang, Shaobin, Siddiqui, Sarah, Bian, Yao, Zhao, Jie, Wang, Chyung-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896622/
https://www.ncbi.nlm.nih.gov/pubmed/27272249
http://dx.doi.org/10.1371/journal.ppat.1005688