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Nonclassical MHC Ib-restricted CD8(+) T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection
MHC Ib-restricted CD8(+) T cells have been implicated in host defense against Mycobacterium tuberculosis (Mtb) infection. However, the relative contribution of various MHC Ib-restricted T cell populations to anti-mycobacterial immunity remains elusive. In this study, we used mice that lack MHC Ia (K...
Autores principales: | Shang, Shaobin, Siddiqui, Sarah, Bian, Yao, Zhao, Jie, Wang, Chyung-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896622/ https://www.ncbi.nlm.nih.gov/pubmed/27272249 http://dx.doi.org/10.1371/journal.ppat.1005688 |
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