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Ca(v)1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice

Retinitis pigmentosa is an inherited blinding disorder characterized by progressive degeneration and loss of photoreceptors. The exact mechanism of degeneration and cell death of photoreceptors is not known, but is thought to involve disturbed Ca(2+)—signaling. Ca(2+) can enter the photoreceptor cel...

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Detalles Bibliográficos
Autores principales: Schön, Christian, Paquet-Durand, François, Michalakis, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896623/
https://www.ncbi.nlm.nih.gov/pubmed/27270916
http://dx.doi.org/10.1371/journal.pone.0156974