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Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy

This commentary describes a rationale for the use of breakthrough viruses from clinical trial participants to assess neutralizing antibodies as a correlate of HIV-1 vaccine efficacy. The rationale is based on principles of a genetic sieve analysis, where the 2 analyses may be cooperative for delinea...

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Detalles Bibliográficos
Autor principal: Montefiori, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896798/
https://www.ncbi.nlm.nih.gov/pubmed/25424964
http://dx.doi.org/10.4161/hv.28950