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Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy
This commentary describes a rationale for the use of breakthrough viruses from clinical trial participants to assess neutralizing antibodies as a correlate of HIV-1 vaccine efficacy. The rationale is based on principles of a genetic sieve analysis, where the 2 analyses may be cooperative for delinea...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896798/ https://www.ncbi.nlm.nih.gov/pubmed/25424964 http://dx.doi.org/10.4161/hv.28950 |