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High-resolution biophysical analysis of the dynamics of nucleosome formation

We describe a biophysical approach that enables changes in the structure of DNA to be followed during nucleosome formation in in vitro reconstitution with either the canonical “Widom” sequence or a judiciously mutated sequence. The rapid non-perturbing photochemical analysis presented here provides...

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Detalles Bibliográficos
Autores principales: Hatakeyama, Akiko, Hartmann, Brigitte, Travers, Andrew, Nogues, Claude, Buckle, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897087/
https://www.ncbi.nlm.nih.gov/pubmed/27263658
http://dx.doi.org/10.1038/srep27337