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Notable Stabilization of α-Chymotrypsin by the Protic Ionic Additive, [ch][dhp]: Calorimetric Evidence for a Fine Enthalpy/Entropy Balance

An impact of 0.5 to 3 M choline dihydrogen phosphate, [ch][dhp], the biotechnologically relevant ionic substance, on the thermal stability of a model globular protein, α-chymotrypsin (α-CT), has been studied exploiting the highly sensitive differential scanning calorimetry (DSC) technique. The notab...

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Detalles Bibliográficos
Autores principales: Uchaneishvili, Sophio, Makharadze, Maya, Shushanyan, Mikhael, van Eldik, Rudi, Khoshtariya, Dimitri E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897175/
https://www.ncbi.nlm.nih.gov/pubmed/27437474
http://dx.doi.org/10.1155/2014/834189