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Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route

Frovatriptan, a 5-HT(1B) and 5-HT(1D) receptor agonist, is used for the treatment of acute migraine attack. This molecule is classified into second line therapy because of its slow onset of action (peak response obtained after 4 hours of administration) and low bioavailability (25%). Moreover, its t...

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Detalles Bibliográficos
Autores principales: Verma, Hitesh, Verma, Surajpal, Prasad, Shyam Baboo, Singh, Harmanpreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897358/
https://www.ncbi.nlm.nih.gov/pubmed/27433492
http://dx.doi.org/10.1155/2014/675868