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Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route
Frovatriptan, a 5-HT(1B) and 5-HT(1D) receptor agonist, is used for the treatment of acute migraine attack. This molecule is classified into second line therapy because of its slow onset of action (peak response obtained after 4 hours of administration) and low bioavailability (25%). Moreover, its t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897358/ https://www.ncbi.nlm.nih.gov/pubmed/27433492 http://dx.doi.org/10.1155/2014/675868 |