Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing

Differentiated somatic cells can be reprogrammed into totipotent embryos through somatic cell nuclear transfer. However, most cloned embryos arrest at early stages and the underlying molecular mechanism remains largely unexplored. Here, we first developed a somatic cell nuclear transfer embryo biops...

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Detalles Bibliográficos
Autores principales: Liu, Wenqiang, Liu, Xiaoyu, Wang, Chenfei, Gao, Yawei, Gao, Rui, Kou, Xiaochen, Zhao, Yanhong, Li, Jingyi, Wu, You, Xiu, Wenchao, Wang, Su, Yin, Jiqing, Liu, Wei, Cai, Tao, Wang, Hong, Zhang, Yong, Gao, Shaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897595/
https://www.ncbi.nlm.nih.gov/pubmed/27462457
http://dx.doi.org/10.1038/celldisc.2016.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897595/
https://www.ncbi.nlm.nih.gov/pubmed/27462457
http://dx.doi.org/10.1038/celldisc.2016.10

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