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Does advancing male age influence the expression levels and localisation patterns of phospholipase C zeta (PLCζ) in human sperm?

Socio-economic factors have led to an increasing trend for couples to delay parenthood. However, advancing age exerts detrimental effects upon gametes which can have serious consequences upon embryo viability. While such effects are well documented for the oocyte, relatively little is known with reg...

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Detalles Bibliográficos
Autores principales: Yeste, Marc, Jones, Celine, Amdani, Siti Nornadhirah, Yelumalai, Suseela, Mounce, Ginny, da Silva, Sarah J. Martins, Child, Tim, Coward, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897631/
https://www.ncbi.nlm.nih.gov/pubmed/27270687
http://dx.doi.org/10.1038/srep27543