Cinnamaldehyde and allopurinol reduce fructose-induced cardiac inflammation and fibrosis by attenuating CD36-mediated TLR4/6-IRAK4/1 signaling to suppress NLRP3 inflammasome activation

Fructose consumption induces metabolic syndrome to increase cardiovascular disease risk. Cinnamaldehyde and allopurinol possess anti-oxidative and anti-inflammatory activity to relieve heart injury in metabolic syndrome. But the mechanisms of fructose-induced cardiac injury, and cardioprotective eff...

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Detalles Bibliográficos
Autores principales: Kang, Lin-Lin, Zhang, Dong-Mei, Ma, Chun-Hua, Zhang, Jian-Hua, Jia, Ke-Ke, Liu, Jia-Hui, Wang, Rong, Kong, Ling-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897702/
https://www.ncbi.nlm.nih.gov/pubmed/27270216
http://dx.doi.org/10.1038/srep27460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897702/
https://www.ncbi.nlm.nih.gov/pubmed/27270216
http://dx.doi.org/10.1038/srep27460

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