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Unravelling the structural plasticity of stretched DNA under torsional constraint

Regions of the genome are often held under torsional constraint. Nevertheless, the influence of such constraint on DNA–protein interactions during genome metabolism is still poorly understood. Here using a combined optical tweezers and fluorescence microscope, we quantify and explain how torsional c...

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Detalles Bibliográficos
Autores principales: King, Graeme A., Peterman, Erwin J. G., Wuite, Gijs J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897764/
https://www.ncbi.nlm.nih.gov/pubmed/27263853
http://dx.doi.org/10.1038/ncomms11810