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The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1

Hepatitis E virus (HEV) genotype 1 infection is common and can emerge as outbreaks in developing areas, thus posing a threat to public health. However, due to the absence of feasible animal models, the mechanism of HE pathogenesis remains obscure. The HEV pathogenic mechanism has been suggested to b...

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Detalles Bibliográficos
Autores principales: He, Man, Wang, Min, Huang, Ying, Peng, Wenju, Zheng, Zizheng, Xia, Ningshao, Xu, Jian, Tian, Deying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897786/
https://www.ncbi.nlm.nih.gov/pubmed/27270888
http://dx.doi.org/10.1038/srep27597