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Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury

BACKGROUND: Methyl-CpG-binding protein 2 (MeCP2), a protein with affinity for methylated cytosines, is crucial for neuronal development and function. MeCP2 regulates gene expression through activation, repression and chromatin remodeling. Mutations in MeCP2 cause Rett syndrome, and these patients di...

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Detalles Bibliográficos
Autores principales: Manners, Melissa T., Ertel, Adam, Tian, Yuzhen, Ajit, Seena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897807/
https://www.ncbi.nlm.nih.gov/pubmed/27279901
http://dx.doi.org/10.1186/s13072-016-0073-5