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Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non–small cell lung cancer cells

BACKGROUND: Radiotherapy is one of the main therapeutic approaches for non–small cell lung cancer (NSCLC). However, radioresistant cancer cells can eventually cause tumor relapse and even fatal metastasis. It is thought that radioresistance and metastasis could be potentially linked by epithelial-me...

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Detalles Bibliográficos
Autores principales: Yao, Yuan-Hu, Cui, Yan, Qiu, Xiang-Nan, Zhang, Long-Zhen, Zhang, Wei, Li, Hao, Yu, Jin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897817/
https://www.ncbi.nlm.nih.gov/pubmed/27266881
http://dx.doi.org/10.1186/s40880-016-0113-3