Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages

BACKGROUND: The aim of this study was to assess the effects of soluble sialic acid-binding immunoglobulin-type lectin (sSiglec)-9 on joint inflammation and destruction in a murine collagen-induced arthritis (CIA) model and in monolayer cultures of murine macrophages (RAW264.7 cells and peritoneal ma...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takuya, Takahashi, Nobunori, Kojima, Toshihisa, Yoshioka, Yutaka, Ishikawa, Jun, Furukawa, Koichi, Ono, Kenji, Sawada, Makoto, Ishiguro, Naoki, Yamamoto, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897938/
https://www.ncbi.nlm.nih.gov/pubmed/27267914
http://dx.doi.org/10.1186/s13075-016-1035-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897938/
https://www.ncbi.nlm.nih.gov/pubmed/27267914
http://dx.doi.org/10.1186/s13075-016-1035-9

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