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Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages
BACKGROUND: The aim of this study was to assess the effects of soluble sialic acid-binding immunoglobulin-type lectin (sSiglec)-9 on joint inflammation and destruction in a murine collagen-induced arthritis (CIA) model and in monolayer cultures of murine macrophages (RAW264.7 cells and peritoneal ma...
Autores principales: | Matsumoto, Takuya, Takahashi, Nobunori, Kojima, Toshihisa, Yoshioka, Yutaka, Ishikawa, Jun, Furukawa, Koichi, Ono, Kenji, Sawada, Makoto, Ishiguro, Naoki, Yamamoto, Akihito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897938/ https://www.ncbi.nlm.nih.gov/pubmed/27267914 http://dx.doi.org/10.1186/s13075-016-1035-9 |
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