Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line

Objective: A non-synonymous single nucleotide polymorphism (nsSNP, rs2233434, Val194Ala) in the NFKBIE (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon) gene is known to be a rheumatoid arthritis (RA) susceptibility polymorphism in the Japanese RA population and...

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Detalles Bibliográficos
Autores principales: Imamura, Hitoshi, Yoshina, Sawako, Ikari, Katsunori, Miyazawa, Keiji, Momohara, Shigeki, Mitani, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898165/
https://www.ncbi.nlm.nih.gov/pubmed/26587663
http://dx.doi.org/10.3109/14397595.2015.1112481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898165/
https://www.ncbi.nlm.nih.gov/pubmed/26587663
http://dx.doi.org/10.3109/14397595.2015.1112481

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