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Strong preference of BRCA1 protein to topologically constrained non-B DNA structures
BACKGROUND: The breast and ovarian cancer susceptibility gene BRCA1 encodes a multifunctional tumor suppressor protein BRCA1, which is involved in regulating cellular processes such as cell cycle, transcription, DNA repair, DNA damage response and chromatin remodeling. BRCA1 protein, located primari...
Autores principales: | Brázda, Václav, Hároníková, Lucia, Liao, Jack C. C., Fridrichová, Helena, Jagelská, Eva B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898351/ https://www.ncbi.nlm.nih.gov/pubmed/27277344 http://dx.doi.org/10.1186/s12867-016-0068-6 |
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