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Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP expression

Cisplatin resistance is a main clinical problem of lung cancer therapy. Gambogic acid (GA) could prohibit the proliferation of a variety of human cancer cells. However, the effects of GA on cisplatin-resistant lung cancer are still unclear. The objective of the present study was to find out the anti...

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Detalles Bibliográficos
Autores principales: Zhang, Wendian, Zhou, Hechao, Yu, Ying, Li, Jingjing, Li, Haiwen, Jiang, Danxian, Chen, Zihong, Yang, Donghong, Xu, Zumin, Yu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898431/
https://www.ncbi.nlm.nih.gov/pubmed/27330316
http://dx.doi.org/10.2147/OTT.S100936