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Anti-platelet activity of panaxatriol saponins is mediated by suppression of intracellular calcium mobilization and ERK2/p38 activation

BACKGROUND: Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main components extracted from Panax notoginseng, has been shown to be efficacious in the prevention and treatment...

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Detalles Bibliográficos
Autores principales: Qi, Hongyi, Huang, Yongliang, Yang, Yi, Dou, Guojun, Wan, Fang, Zhang, Wenwu, Yang, Huarong, Wang, Li, Wu, Chunjie, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898458/
https://www.ncbi.nlm.nih.gov/pubmed/27277000
http://dx.doi.org/10.1186/s12906-016-1160-7