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Coupling the folding of a β-hairpin with chelation-enhanced luminescence of Tb(iii) and Eu(iii) ions for specific sensing of a viral RNA
Rational modification of a natural RNA-binding peptide with a lanthanide EDTA chelator, and a phenanthroline ligand yields a highly selective luminescent sensor. The sensing mechanism relies on the RNA-triggered folding of the peptide into a β-hairpin, which promotes the coordination of the phenanth...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898589/ https://www.ncbi.nlm.nih.gov/pubmed/27293537 http://dx.doi.org/10.1039/c5sc04501k |