Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures

Topical preexposure prophylaxis (PrEP) against HIV has been marginally successful in recent clinical trials with low adherence rates being a primary factor for failure. Controlled, sustained release of antiretroviral (ARV) drugs may help overcome these low adherence rates if the product is protectiv...

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Detalles Bibliográficos
Autores principales: Srinivasan, Priya, Moss, John A., Gunawardana, Manjula, Churchman, Scott A., Yang, Flora, Dinh, Chuong T., Mitchell, James M., Zhang, Jining, Fanter, Rob, Miller, Christine S., Butkyavichene, Irina, McNicholl, Janet M., Smith, Thomas J., Baum, Marc M., Smith, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898685/
https://www.ncbi.nlm.nih.gov/pubmed/27275923
http://dx.doi.org/10.1371/journal.pone.0157061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898685/
https://www.ncbi.nlm.nih.gov/pubmed/27275923
http://dx.doi.org/10.1371/journal.pone.0157061

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