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Functional Characterization of Schizophrenia-Associated Variation in CACNA1C

Calcium channel subunits, including CACNA1C, have been associated with multiple psychiatric disorders. Specifically, genome wide association studies (GWAS) have repeatedly identified the single nucleotide polymorphism (SNP) rs1006737 in intron 3 of CACNA1C to be strongly associated with schizophreni...

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Detalles Bibliográficos
Autores principales: Eckart, Nicole, Song, Qifeng, Yang, Rebecca, Wang, Ruihua, Zhu, Heng, McCallion, Andrew S., Avramopoulos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898738/
https://www.ncbi.nlm.nih.gov/pubmed/27276213
http://dx.doi.org/10.1371/journal.pone.0157086