Adult Restoration of Shank3 Expression Rescues Selective Autistic-Like Phenotypes

Because ASD is a neurodevelopmental disorder and patients typically display symptoms before the age of three(1), one of the key questions in autism research is whether the pathology is reversible in adults. Here we investigated the developmental requirement of Shank3, one of the most prominent monog...

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Detalles Bibliográficos
Autores principales: Mei, Yuan, Monteiro, Patricia, Zhou, Yang, Kim, Jin-Ah, Gao, Xian, Fu, Zhanyan, Feng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898763/
https://www.ncbi.nlm.nih.gov/pubmed/26886798
http://dx.doi.org/10.1038/nature16971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898763/
https://www.ncbi.nlm.nih.gov/pubmed/26886798
http://dx.doi.org/10.1038/nature16971

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