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The Somatic Nature of Cancer Allows It to Affect Highly Constrained Genes
Cancer is special among genetic disorders in two major ways: first, cancer is a disease of the most basic of cellular functions, such as cell proliferation, differentiation, and the maintenance of genomic integrity. Second, in contrast to most genetic disorders that are mediated by germline (heredit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898816/ https://www.ncbi.nlm.nih.gov/pubmed/27190005 http://dx.doi.org/10.1093/gbe/evw110 |