Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils

IL-5-induced chemotaxis of eosinophils is an important feature of allergic airway inflammatory diseases. Simvastatin, a lipid lowering agent, has been shown to exhibit anti-inflammatory and anti-allergic effects. Our aim was to investigate the effect of simvastatin on IL-5-induced eosinophil chemota...

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Detalles Bibliográficos
Autores principales: Fu, Chia-Hsiang, Tsai, Wan-Chun, Lee, Ta-Jen, Huang, Chi-Che, Chang, Po-Hung, Su Pang, Jong-Hwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898827/
https://www.ncbi.nlm.nih.gov/pubmed/27275740
http://dx.doi.org/10.1371/journal.pone.0157186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898827/
https://www.ncbi.nlm.nih.gov/pubmed/27275740
http://dx.doi.org/10.1371/journal.pone.0157186

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