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Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function

Cochlear hair cells convert sound-induced vibration into electrical signals. FAM65B mutations cause hearing loss by an unknown mechanism. Using biochemistry and stochastic optical reconstruction microscopy (STORM), we show here that Fam65b oligomers form a circumferential ring near the basal taper o...

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Detalles Bibliográficos
Autores principales: Zhao, Bo, Wu, Zizhen, Müller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898930/
https://www.ncbi.nlm.nih.gov/pubmed/27269051
http://dx.doi.org/10.7554/eLife.14222