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Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function
Cochlear hair cells convert sound-induced vibration into electrical signals. FAM65B mutations cause hearing loss by an unknown mechanism. Using biochemistry and stochastic optical reconstruction microscopy (STORM), we show here that Fam65b oligomers form a circumferential ring near the basal taper o...
Autores principales: | Zhao, Bo, Wu, Zizhen, Müller, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898930/ https://www.ncbi.nlm.nih.gov/pubmed/27269051 http://dx.doi.org/10.7554/eLife.14222 |
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