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Distinct responses to reduplicated chromosomes require distinct Mad2 responses

Duplicating chromosomes once each cell cycle produces sister chromatid pairs, which separate accurately at anaphase. In contrast, reduplicating chromosomes without separation frequently produces polytene chromosomes, a barrier to accurate mitosis. Chromosome reduplication occurs in many contexts, in...

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Detalles Bibliográficos
Autores principales: Stormo, Benjamin M, Fox, Donald T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898934/
https://www.ncbi.nlm.nih.gov/pubmed/27159240
http://dx.doi.org/10.7554/eLife.15204