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Sorafenib treatment in children with relapsed and refractory neuroblastoma: an experience of four cases

Metastatic neuroblastoma is an aggressive malignancy with a poor prognosis. Recent findings have shown that sorafenib decreases cell viability and increases apoptosis in human neuroblastoma cell lines. We report an experience of compassionate use of sorafenib in children with treatment‐refractory ne...

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Detalles Bibliográficos
Autores principales: Okada, Keiko, Nakano, Yoshiko, Yamasaki, Kai, Nitani, Chika, Fujisaki, Hiroyuki, Hara, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898977/
https://www.ncbi.nlm.nih.gov/pubmed/27264843
http://dx.doi.org/10.1002/cam4.784