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Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis

There is an urgent need to improve the quality of donor organs obtained after cardiac death. In the present study, we examined the potential mechanisms through which A20 protects renal cells against ischemia/reperfusion injury (IRI) following either hypothermic machine perfusion (HMP) or static cold...

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Detalles Bibliográficos
Autores principales: YANG, ZIXUAN, ZHONG, ZIBIAO, LI, MINGXIA, XIONG, YAN, WANG, YANFENG, PENG, GUIZHU, YE, QIFA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899006/
https://www.ncbi.nlm.nih.gov/pubmed/27177159
http://dx.doi.org/10.3892/ijmm.2016.2586