CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1

The CD5 transmembrane glycoprotein functions as a co-receptor in the signaling pathway linking T-cell antigen receptor (TCR) engagement to activation and differentiation. Although CD5 effects on TCR signaling have been shown to be primarily inhibitory, the underlying mechanisms remain unclear. In vi...

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Detalles Bibliográficos
Autores principales: DONG, BAOXIA, SOMANI, ALLY-KHAN, LOVE, PAUL E., ZHENG, XUAN, CHEN, XIEQUN, ZHANG, JINYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899029/
https://www.ncbi.nlm.nih.gov/pubmed/27221212
http://dx.doi.org/10.3892/ijmm.2016.2592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899029/
https://www.ncbi.nlm.nih.gov/pubmed/27221212
http://dx.doi.org/10.3892/ijmm.2016.2592

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