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Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1

Pancreatic cancer has a poor prognosis. It is reported that the PI3K/Akt pathway is activated in many cancers, and inhibition of the PI3K/Akt pathway can induce cell apoptosis in most cancers. Polo-like kinase 1 (Plk1) is also overexpressed in most malignancies, and it controls multiple aspects of m...

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Detalles Bibliográficos
Autores principales: MAO, YONGHUAN, XI, LING, LI, QUAN, CAI, ZELING, LAI, YIMEI, ZHANG, XINHUA, YU, CHUNZHAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899032/
https://www.ncbi.nlm.nih.gov/pubmed/27220401
http://dx.doi.org/10.3892/or.2016.4820