FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)

Fibroblast growth factor (FGF)2, FGF4, FGF7 and FGF20 are representative paracrine FGFs binding to heparan-sulfate proteoglycan and fibroblast growth factor receptors (FGFRs), whereas FGF19, FGF21 and FGF23 are endocrine FGFs binding to Klotho and FGFRs. FGFR1 is relatively frequently amplified and...

Descripción completa

Detalles Bibliográficos
Autor principal: KATOH, MASARU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899036/
https://www.ncbi.nlm.nih.gov/pubmed/27245147
http://dx.doi.org/10.3892/ijmm.2016.2620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899036/
https://www.ncbi.nlm.nih.gov/pubmed/27245147
http://dx.doi.org/10.3892/ijmm.2016.2620

Ejemplares similares