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FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)
Fibroblast growth factor (FGF)2, FGF4, FGF7 and FGF20 are representative paracrine FGFs binding to heparan-sulfate proteoglycan and fibroblast growth factor receptors (FGFRs), whereas FGF19, FGF21 and FGF23 are endocrine FGFs binding to Klotho and FGFRs. FGFR1 is relatively frequently amplified and...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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D.A. Spandidos
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899036/ https://www.ncbi.nlm.nih.gov/pubmed/27245147 http://dx.doi.org/10.3892/ijmm.2016.2620 |