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Impact of Pre-adapted HIV Transmission
Human Leukocyte Antigen class I (HLA) restricted CD8(+) T lymphocyte (CTL) responses are critical to HIV-1 control. Although HIV can evade these responses, the longer-term impact of viral escape mutants remains unclear, since these variants can also reduce intrinsic viral fitness. To address this qu...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899163/ https://www.ncbi.nlm.nih.gov/pubmed/27183217 http://dx.doi.org/10.1038/nm.4100 |