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Impact of Pre-adapted HIV Transmission

Human Leukocyte Antigen class I (HLA) restricted CD8(+) T lymphocyte (CTL) responses are critical to HIV-1 control. Although HIV can evade these responses, the longer-term impact of viral escape mutants remains unclear, since these variants can also reduce intrinsic viral fitness. To address this qu...

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Detalles Bibliográficos
Autores principales: Carlson, Jonathan M., Du, Victor Y., Pfeifer, Nico, Bansal, Anju, Tan, Vincent Y.F., Power, Karen, Brumme, Chanson J., Kreimer, Anat, DeZiel, Charles E., Fusi, Nicolo, Schaefer, Malinda, Brockman, Mark A., Gilmour, Jill, Price, Matt A., Kilembe, William, Haubrich, Richard, John, Mina, Mallal, Simon, Shapiro, Roger, Frater, John, Harrigan, P. Richard, Ndung’u, Thumbi, Allen, Susan, Heckerman, David, Sidney, John, Allen, Todd M., Goulder, Philip J.R., Brumme, Zabrina L., Hunter, Eric, Goepfert, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899163/
https://www.ncbi.nlm.nih.gov/pubmed/27183217
http://dx.doi.org/10.1038/nm.4100

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