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BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin
Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers. Whereas chromatin de-compaction and transcriptional activation of target genes are associated with BRD4 bi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899182/ https://www.ncbi.nlm.nih.gov/pubmed/27159561 http://dx.doi.org/10.1038/nsmb.3228 |