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Extensive subunit contacts underpin herpesvirus capsid stability and interior-to-exterior allostery

The herpesvirus capsid is a complex protein assembly that includes hundreds of copies of four major subunits and lesser numbers of several minor proteins, all essential for infectivity. Cryo-electron microscopy is uniquely suited for studying interactions that govern the assembly and function of suc...

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Detalles Bibliográficos
Autores principales: Huet, Alexis, Makhov, Alexander M., Huffman, Jamie B., Vos, Matthijn, Homa, Fred L., Conway, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899274/
https://www.ncbi.nlm.nih.gov/pubmed/27111889
http://dx.doi.org/10.1038/nsmb.3212