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Cocaine Enhances HIV-1 Transcription in Macrophages by Inducing p38 MAPK Phosphorylation

Cocaine is a commonly used illicit drug among HIV-1 infected individuals and is known to increase HIV-1 replication in permissive cells including PBMCs, CD4(+) T cells, and macrophages. Cocaine’s potentiating effects on HIV-1 replication in macrophages- the primary targets of the virus in the centra...

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Detalles Bibliográficos
Autores principales: Swepson, Chelsie, Ranjan, Alok, Balasubramaniam, Muthukumar, Pandhare, Jui, Dash, Chandravanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899462/
https://www.ncbi.nlm.nih.gov/pubmed/27375565
http://dx.doi.org/10.3389/fmicb.2016.00823