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Cinnamomum verum component 2-methoxycinnamaldehyde: a novel antiproliferative drug inducing cell death through targeting both topoisomerase I and II in human colorectal adenocarcinoma COLO 205 cells

BACKGROUND: Cinnamomum verum is used to manufacture the spice cinnamon. In addition, the plant has been used as a Chinese herbal medication. METHODS: We investigated the antiproliferative effect of 2-methoxycinnamaldehyde (2-MCA), a constituent of the cortex of the plant, and the molecular biomarker...

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Detalles Bibliográficos
Autores principales: Tsai, Kuen-daw, Cherng, Jonathan, Liu, Yi-Heng, Chen, Ta-Wei, Wong, Ho-Yiu, Yang, Shu-mei, Chou, Kuo-Shen, Cherng, Jaw-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899521/
https://www.ncbi.nlm.nih.gov/pubmed/27281694
http://dx.doi.org/10.3402/fnr.v60.31607