Cargando…

Cinnamomum verum component 2-methoxycinnamaldehyde: a novel antiproliferative drug inducing cell death through targeting both topoisomerase I and II in human colorectal adenocarcinoma COLO 205 cells

BACKGROUND: Cinnamomum verum is used to manufacture the spice cinnamon. In addition, the plant has been used as a Chinese herbal medication. METHODS: We investigated the antiproliferative effect of 2-methoxycinnamaldehyde (2-MCA), a constituent of the cortex of the plant, and the molecular biomarker...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Kuen-daw, Cherng, Jonathan, Liu, Yi-Heng, Chen, Ta-Wei, Wong, Ho-Yiu, Yang, Shu-mei, Chou, Kuo-Shen, Cherng, Jaw-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Co-Action Publishing 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899521/ https://www.ncbi.nlm.nih.gov/pubmed/27281694 http://dx.doi.org/10.3402/fnr.v60.31607

Ejemplares similares

Cuminaldehyde from Cinnamomum verum Induces Cell Death through Targeting Topoisomerase 1 and 2 in Human Colorectal Adenocarcinoma COLO 205 Cells
por: Tsai, Kuen-daw, et al.
Publicado: (2016)

Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde
por: Perng, Daw-Shyong, et al.
Publicado: (2016)

Molecular Mechanism of Cinnamomum verum Component Cuminaldehyde Inhibits Cell Growth and Induces Cell Death in Human Lung Squamous Cell Carcinoma NCI-H520 Cells In Vitro and In Vivo
por: Yang, Shu-mei, et al.
Publicado: (2016)

Synergistic Action of Cinnamomum verum Essential Oil with Sertraline
por: Barbarossa, Alexia, et al.
Publicado: (2022)

Protective effects of 2-methoxycinnamaldehyde an active ingredients of Cinnamomum cassia on warm hepatic ischemia reperfusion injury in rat model
por: Golshahi, Hannaneh, et al.
Publicado: (2019)

Chemical composition and tyrosinase inhibitory activity of Cinnamomum cassia essential oil
por: Chang, Chen-Tien, et al.
Publicado: (2013)

Cinnamomum verum J. Presl Bark Contains High Contents of Nicotinamide Mononucleotide
por: Yan, Jing, et al.
Publicado: (2022)

Macroscopic and microscopic study on floral biology and pollination of Cinnamomum verum Blume (Sri Lankan)
por: Hathurusinghe, Bhagya M., et al.
Publicado: (2023)

Contribution to the improvement of the nutritional and functional properties of bread by incorporating cinnamon powder (Cinnamomum verum)
por: Bouatenin, Koffi Maïzan Jean‐Paul, et al.
Publicado: (2023)

Evaluation of Ethanol and Aqueous extracts of Cinnamomum verum Leaf Galls for Potential Antioxidant and Analgesic activity
por: Pandey, Minakshi, et al.
Publicado: (2015)

Cinnamomum verum Bark Extract Mediated Green Synthesis of ZnO Nanoparticles and Their Antibacterial Potentiality
por: Ansari, Mohammad Azam, et al.
Publicado: (2020)

Phytochemical Characterization and Chemotherapeutic Potential of Cinnamomum verum Extracts on the Multiplication of Protozoan Parasites In Vitro and In Vivo
por: Batiha, Gaber El-Saber, et al.
Publicado: (2020)

Essential Oil Chemotypes and Genetic Variability of Cinnamomum verum Leaf Samples Commercialized and Cultivated in the Amazon
por: Xavier, Júlia Karla A. M., et al.
Publicado: (2022)

Anti-Candida and Anti-Leishmanial Activities of Encapsulated Cinnamomum verum Essential Oil in Chitosan Nanoparticles
por: Essid, Rym, et al.
Publicado: (2023)

Cultivation and identification of colon cancer stem cell-derived spheres from the Colo205 cell line
por: Li, Ying-fei, et al.
Publicado: (2012)

Metabolomics-Driven Exploration of the Antibacterial Activity and Mechanism of 2-Methoxycinnamaldehyde
por: Qian, Chunguo, et al.
Publicado: (2022)

Anthelmintic activity of trans-cinnamaldehyde and A- and B-type proanthocyanidins derived from cinnamon (Cinnamomum verum)
por: Williams, Andrew R., et al.
Publicado: (2015)

MAPLE Fabricated Fe(3)O(4)@Cinnamomum verum Antimicrobial Surfaces for Improved Gastrostomy Tubes
por: Anghel, Alina Georgiana, et al.
Publicado: (2014)

Anticoccidial effectivity of a traditional medicinal plant, Cinnamomum verum, in broiler chickens infected with Eimeria tenella
por: Qaid, Mohammed M., et al.
Publicado: (2020)

Chemical Composition of Cinnamomum verum Leaf and Flower Essential Oils and Analysis of Their Antibacterial, Insecticidal, and Larvicidal Properties
por: Narayanankutty, Arunaksharan, et al.
Publicado: (2021)

Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping
por: Sharma, Vivek K., et al.
Publicado: (2022)

Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205
por: Flis, Sylwia, et al.
Publicado: (2009)

Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase
por: Choi, Hyun-Myung, et al.
Publicado: (2016)

Efficacy of true cinnamon (Cinnamomum verum) leaf essential oil as a therapeutic alternative for Candida biofilm infections
por: Wijesinghe, Gayan Kanchana, et al.
Publicado: (2021)

Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro
por: Olszewski, Ulrike, et al.
Publicado: (2011)

Wnt/β-catenin signaling pathway is involved in induction of apoptosis by oridonin in colon cancer COLO205 cells
por: Bu, Heqi, et al.
Publicado: (2019)

In vitro biological evaluation of eight different essential oils against Trypanosoma cruzi, with emphasis on Cinnamomum verum essential oil
por: Azeredo, Camila Maria O, et al.
Publicado: (2014)

Assessing the Ameliorative Effect of Selenium Cinnamomum verum, Origanum majorana, and Origanum vulgare Nanoparticles in Diabetic Zebrafish (Danio rerio)
por: Pérez Gutiérrez, Rosa Martha, et al.
Publicado: (2022)

Antioxidant and Anti-Inflammatory Effect of Cinnamon (Cinnamomum verum J. Presl) Bark Extract after In Vitro Digestion Simulation
por: Pagliari, Stefania, et al.
Publicado: (2023)

Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte Activation
por: Lee, Hyun-Su, et al.
Publicado: (2015)

The Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line
por: Abdullah, Murdani, et al.
Publicado: (2017)

Effect of Cinnamomum Verum Extract on the Amyloid Formation of Hen Egg-white Lysozyme and Study of its Possible Role in Alzheimer’s Disease
por: Ramshini, Hassan, et al.
Publicado: (2015)

Effect of Cinnamomum verum leaf essential oil on virulence factors of Candida species and determination of the in-vivo toxicity with Galleria mellonella model
por: Wijesinghe, Gayan Kanchana, et al.
Publicado: (2020)

Endophytic Trichoderma Species Isolated from Persea americana and Cinnamomum verum Roots Reduce Symptoms Caused by Phytophthora cinnamomi in Avocado
por: Andrade-Hoyos, Petra, et al.
Publicado: (2020)

Macro‑micro‑morphological diagnosis of leaves of two species of Cinnamomum (C. sulphuratum and C. verum) used as resource of bay leaf
por: Narayana, Sunil Kumar Koppala, et al.
Publicado: (2019)

Analysis of the effectiveness of cinnamon (Cinnamomum verum) in the reduction of glycemic and lipidic levels of adults with type 2 diabetes: A study protocol
por: Neto, José Claudio Garcia Lira, et al.
Publicado: (2020)

Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity
por: Saeedi, Mina, et al.
Publicado: (2022)

Quaere verum
por: Trimble, Michael
Publicado: (2022)

Marum Verum
por: Pehrson,
Publicado: (1887)

Brefeldin A Effectively Inhibits Cancer Stem Cell-Like Properties and MMP-9 Activity in Human Colorectal Cancer Colo 205 Cells
por: Tseng, Chao-Neng, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_855fmogotlo3rtf2lksgc2hk4v