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Bioinformatic Analysis of the Human Recombinant Iduronate 2-Sulfate Sulfatase

Mucopolysaccharidosis type II is a human recessive disease linked to the X chromosome caused by deficiency of lysosomal enzyme Iduronate 2-Sulfate Sulfatase (IDS), which leads to accumulation of glycosaminoglycans in tissues and organs. The human enzyme has been expressed in Escherichia coli and Pic...

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Detalles Bibliográficos
Autores principales: Morales-Álvarez, Edwin D., Rivera-Hoyos, Claudia M., Landázuri, Patricia, Poutou-Piñales, Raúl A., Pedroza-Rodríguez, Aura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899537/
https://www.ncbi.nlm.nih.gov/pubmed/27335624
http://dx.doi.org/10.2174/1874285801610010124