Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells

Molecular targeting for the altered signaling pathways has been proven to be effective for the treatment ofmany types of human cancer, including colorectal cancer (CRC). The dual phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 has shown to exhibit poten...

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Detalles Bibliográficos
Autores principales: Oh, Iljoong, Cho, Hyunchul, Lee, Yonghoon, Cheon, Minseok, Park, Deokbae, Lee, Youngki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Developmental Biology 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899554/
https://www.ncbi.nlm.nih.gov/pubmed/27294206
http://dx.doi.org/10.12717/DR.2016.20.1.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899554/
https://www.ncbi.nlm.nih.gov/pubmed/27294206
http://dx.doi.org/10.12717/DR.2016.20.1.001

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