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Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells
Molecular targeting for the altered signaling pathways has been proven to be effective for the treatment ofmany types of human cancer, including colorectal cancer (CRC). The dual phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 has shown to exhibit poten...
Autores principales: | Oh, Iljoong, Cho, Hyunchul, Lee, Yonghoon, Cheon, Minseok, Park, Deokbae, Lee, Youngki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Developmental Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899554/ https://www.ncbi.nlm.nih.gov/pubmed/27294206 http://dx.doi.org/10.12717/DR.2016.20.1.001 |
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