A Combination of Targeted Therapy with Chemotherapy Backbone Induces Response in a Treatment-Resistant Triple-Negative MCL1-Amplified Metastatic Breast Cancer Patient

After failure of anthracycline- and platinum-based therapy, no effective therapies exist for management of metastatic triple-negative breast cancer (TNBC). We report a case of metastatic TNBC harboring MCL1 amplification, as identified by comprehensive genomic profiling in the course of clinical car...

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Detalles Bibliográficos
Autores principales: Ali, Siraj M., Watson, Jessica, Wang, Kai, Chung, Jon H., McMahon, Caitlin, Ross, Jeffrey S., Dicke, Karel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Published online: February, 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899635/
https://www.ncbi.nlm.nih.gov/pubmed/27293397
http://dx.doi.org/10.1159/000443371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899635/
https://www.ncbi.nlm.nih.gov/pubmed/27293397
http://dx.doi.org/10.1159/000443371

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