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A Combination of Targeted Therapy with Chemotherapy Backbone Induces Response in a Treatment-Resistant Triple-Negative MCL1-Amplified Metastatic Breast Cancer Patient
After failure of anthracycline- and platinum-based therapy, no effective therapies exist for management of metastatic triple-negative breast cancer (TNBC). We report a case of metastatic TNBC harboring MCL1 amplification, as identified by comprehensive genomic profiling in the course of clinical car...
Autores principales: | Ali, Siraj M., Watson, Jessica, Wang, Kai, Chung, Jon H., McMahon, Caitlin, Ross, Jeffrey S., Dicke, Karel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899635/ https://www.ncbi.nlm.nih.gov/pubmed/27293397 http://dx.doi.org/10.1159/000443371 |
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