Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis

Inorganic polyphosphate (PolyP) plays an essential role in microbial stress adaptation, virulence and drug tolerance. The genome of Mycobacterium tuberculosis encodes for two polyphosphate kinases (PPK-1, Rv2984 and PPK-2, Rv3232c) and polyphosphatases (ppx-1, Rv0496 and ppx-2, Rv1026) for maintenan...

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Detalles Bibliográficos
Autores principales: Singh, Mamta, Tiwari, Prabhakar, Arora, Garima, Agarwal, Sakshi, Kidwai, Saqib, Singh, Ramandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899718/
https://www.ncbi.nlm.nih.gov/pubmed/27279366
http://dx.doi.org/10.1038/srep26900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899718/
https://www.ncbi.nlm.nih.gov/pubmed/27279366
http://dx.doi.org/10.1038/srep26900

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