Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1

Acid Sensing Ion Channels (ASICs) detect extracellular proton signals and are involved in synaptic transmission and pain sensation. ASIC subunits assemble into homo- and heteromeric channels composed of three subunits. Single molecule imaging revealed that heteromers composed of ASIC1a and ASIC2a, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Joeres, Niko, Augustinowski, Katrin, Neuhof, Andreas, Assmann, Marc, Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899722/
https://www.ncbi.nlm.nih.gov/pubmed/27277303
http://dx.doi.org/10.1038/srep27647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899722/
https://www.ncbi.nlm.nih.gov/pubmed/27277303
http://dx.doi.org/10.1038/srep27647

Ejemplares similares