Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation

Voltage-gated potassium channels open at depolarized membrane voltages. A prolonged depolarization causes a rearrangement of the selectivity filter which terminates the conduction of ions – a process called slow or C-type inactivation. How structural rearrangements in the voltage-sensor domain (VSD)...

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Detalles Bibliográficos
Autores principales: Conti, Luca, Renhorn, Jakob, Gabrielsson, Anders, Turesson, Fredrik, Liin, Sara I, Lindahl, Erik, Elinder, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899724/
https://www.ncbi.nlm.nih.gov/pubmed/27278891
http://dx.doi.org/10.1038/srep27562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899724/
https://www.ncbi.nlm.nih.gov/pubmed/27278891
http://dx.doi.org/10.1038/srep27562

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